Epigenetics research seeks to describe dynamic alterations in the transcriptional potential of a cell. Changes in the epigenome occur regularly and naturally, but can also be influenced by several factors including age, the environment/lifestyle, and disease state. Epigenomics is believed to be the link between the environment and gene expression. The main epigenetic mechanisms are DNA methylation, histone modification and non-coding RNA-associated gene silencing. NXTGNT has all the tools in house to analyse these epigenetic mechanism in an integrated analysis.

NXTGNT offers services to study all three epigenetic systems in your samples.

For DNA methylation

• MBD sequencing or (h)MeDIP sequencing
• (Oxidative) reduced representation bisulfite sequencing
• (Oxidative) bisulfite sequencing

For histone modifications

• ChIP-seq

For ncRNAs and miRNAs

• RNA-seq

For more information about epigenetics services, feel free to contact us.